ERCO Pharma’s stratum corneum model has been optimized against high resolution cryo-electron microscopy reference data from human skin.
A computational approach enables unmatched versatility during modifications of the concentration of active ingredient and penetrations enhancers.
Data collection with a resolution down to atomic coordinates is utilized in order to give a detailed description of the permeation process.
Using ERCO Pharma’s skin model we can obtain predicted permeation-rates of multiple solutes across the stratum corneum.
Our skin model can help you optimize your topical formulation in order to maximize the partitioning of your drug molecule into human skin.
Assoc. Professor, Ph.D. Dermatologist. 20 years of research experience with a focus on the determination of the structure and formation of the human skin using cryo-EM.
Ph.D., Pharmaceutical Biophysicist, background in organic chemistry and pharmacy, with an extensive experience from MD simulations and various free energy calculations.
Ph.D., Theoretical Biophysicist. background in biotechnology, with previous experience from MD development and permeation calculations across cell membrane models.
M.Sc., Mathematician and programmer. Expert on cryo-EM simulation. Designs software used to construct molecular models as well as analysis of simulation output.